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For research published in Archives of Toxicology in 2020, scientists fed one group of mice a solution containing titanium dioxide for one month, and compared it to those that did not receive the additive. They found “the richness and evenness of gut microbiota were remarkably decreased and the gut microbial community compositions were significantly changed” in the titanium dioxide group when compared with the control group. The tests also revealed that the titanium dioxide exposure could cause locomotor dysfunction, or mobility issues “by elevating the excitement of enteric neurons, which might spread to the brain via gut-brain communication by vagal pathway.” The researchers concluded: “These findings provide valuable insights into the novel mechanism of TiO2NP-induced neurotoxicity. Understanding the microbiota-gut-brain axis will provide the foundation for potential therapeutic or prevention approaches against TiO2NP-induced gut and brain-related disorders.”

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Prof Maged Younes, Chair of EFSA’s expert Panel on Food Additives and Flavourings (FAF), said: “Taking into account all available scientific studies and data, the Panel concluded that titanium dioxide can no longer be considered safe as a food additive . A critical element in reaching this conclusion is that we could not exclude genotoxicity concerns after consumption of titanium dioxide particles. After oral ingestion, the absorption of titanium dioxide particles is low, however they can accumulate in the body”. 

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Traditionally, UV-filters are categorized as either chemical or physical. The big difference is supposed to be that chemical agents absorb UV-light while physical agents reflect it like a bunch of mini umbrellas on top of the skin. While this categorization is easy and logical it turns out it's not true. A recent, 2016 study shows that inorganic sunscreens work mostly by absorption, just like chemical filters, and only a little bit by reflection (they do reflect the light in the visible spectrum, but mostly absorb in the UV spectrum).

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The stability of R-906 rutile titanium dioxide under various printing conditions is another factor contributing to its popularity among ink suppliers. Whether used in offset, flexographic, or gravure printing processes, this pigment maintains its color strength and clarity without fading or discoloration Whether used in offset, flexographic, or gravure printing processes, this pigment maintains its color strength and clarity without fading or discoloration Whether used in offset, flexographic, or gravure printing processes, this pigment maintains its color strength and clarity without fading or discoloration Whether used in offset, flexographic, or gravure printing processes, this pigment maintains its color strength and clarity without fading or discolorationprinting ink grade rutile titanium dioxide r-906 supplier. Moreover, its chemical resistance prevents reactions with other components of the ink, ensuring long-term reliability and reducing the risk of spoilage.

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